clinicaltrials-database

Included with Lifetime

$97 forever

# ClinicalTrials.gov Database

General

What this skill does

# ClinicalTrials.gov Database

Query the U.S. National Library of Medicine's clinical trials registry through API v2. Public access, no authentication required.

## Triggers

- User asks about ongoing or completed clinical trials
- User needs trial details for a specific drug/intervention
- User wants to track recruitment status
- User is analyzing trial landscape for a cardiology topic
- User needs NCT numbers for references

## Core Capabilities

| Function | Description |
|----------|-------------|
| Condition search | Find trials for specific diseases |
| Intervention tracking | Identify trials testing drugs/devices |
| Geographic filtering | Locate trials by region/facility |
| Sponsor lookup | Search by conducting organization |
| Status filtering | Filter by recruitment stage |
| NCT detail retrieval | Full study information via NCT ID |
| CSV export | Download data for analysis |

## API Technical Details

- **Rate limit**: ~50 requests/minute
- **Response formats**: JSON, CSV
- **Max page size**: 1000 studies per request
- **Date format**: ISO 8601

## Example Searches

### Cardiology Trial Discovery

```python
# Find active heart failure trials
GET /studies?query.cond=heart+failure&filter.overallStatus=RECRUITING

# SGLT2 inhibitor trials in cardiology
GET /studies?query.intr=SGLT2+inhibitor&query.cond=cardiovascular

# Trials at major academic centers
GET /studies?query.locn=Cleveland+Clinic&query.cond=coronary+artery+disease

# Phase 3 trials for new anticoagulants
GET /studies?query.intr=anticoagulant&filter.phase=PHASE3
```

### Common Status Values
- `RECRUITING` - Currently enrolling
- `ACTIVE_NOT_RECRUITING` - Ongoing, enrollment closed
- `COMPLETED` - Trial finished
- `TERMINATED` - Stopped early
- `WITHDRAWN` - Never started enrollment

## Workflow Integration

### For Newsletter/Editorial Content
1. Search for recent trial results in target area
2. Identify landmark trials by enrollment size and phase
3. Pull NCT IDs for proper citation
4. Cross-reference with PubMed for published results
5. Note primary endpoints and key secondary outcomes

### For Trial Analysis Pieces
1. Retrieve full study record via NCT ID
2. Extract: design, enrollment, endpoints, sponsor
3. Compare with published results if available
4. Assess trial quality (blinding, randomization, sample size)
5. Contextualize within existing evidence

## Key Fields to Extract

| Field | Use Case |
|-------|----------|
| `briefTitle` | Quick reference |
| `officialTitle` | Full citation |
| `studyType` | Interventional vs observational |
| `phases` | Development stage |
| `enrollmentInfo` | Sample size |
| `primaryOutcomes` | Main endpoints |
| `startDate` / `completionDate` | Timeline |
| `leadSponsor` | Industry vs academic |

## Best Practices

- Always cite NCT number when discussing trials
- Note enrollment numbers for context on power
- Distinguish between primary and secondary endpoints
- Check for related publications in PubMed
- Note funding source for potential bias assessment

Files: 1

Size: 2.9 KB

Complexity: 5/100

Category: General

Source: https://github.com/drshailesh88/integrated_content_os/tree/main/skills/cardiology/clinicaltrials-database

Related in General

modeling-omnistudio-epc-catalog

Included

Salesforce Industries CME EPC product-modeling skill for Product2-based catalog creation. Use when creating EPC products, configuring product attributes, building offer bundles with Product Child Items, or reviewing EPC DataPack JSON metadata for product catalog changes. TRIGGER when: user creates or updates Product2 EPC records, AttributeAssignment payloads, AttributeMetadata/AttributeDefaultValues, Offer bundles, or ProductChildItem relationships. DO NOT TRIGGER when: designing OmniScripts/FlexCards/Integration Procedures (use building-omnistudio-omniscript, building-omnistudio-flexcard, or building-omnistudio-integration-procedure), implementing Apex business logic (use generating-apex), or troubleshooting deployment pipelines (use deploying-metadata).

Generalscripts

relationship-science-coach

Included

Use this skill for direct, practical adult relationship coaching: couples conflict, repair, trust, marriage, dating, flirting, attachment patterns, emotional connection, sex, desire differences, eroticism, kink negotiation, affection, love languages, breakups, and long-term passion. Draw on Gottman, EFT and Hold Me Tight, attachment science, modern sex research, Perel, Nagoski, Kerner, Schnarch, Love and Stosny, and flexible love-language tools. Be concrete and low-hedge. Redirect only for imminent danger, abuse, coercive control, minors, non-consent, self-harm, stalking, or medical/legal/psychiatric decisions.

Generalscripts

building-sf-integrations

Included

Salesforce integration architecture and runtime plumbing with 120-point scoring. Use this skill to set up Named Credentials, External Credentials, External Services, REST/SOAP callout patterns, Platform Events, and Change Data Capture. TRIGGER when: user sets up Named Credentials, External Services, REST/SOAP callouts, Platform Events, CDC, or touches .namedCredential-meta.xml files. DO NOT TRIGGER when: Connected App/OAuth config (use configuring-connected-apps), Apex-only logic (use generating-apex), or data import/export (use handling-sf-data).

Generalscripts

venue-templates

Included

Access comprehensive LaTeX templates, formatting requirements, and submission guidelines for major scientific publication venues (Nature, Science, PLOS, IEEE, ACM), academic conferences (NeurIPS, ICML, CVPR, CHI), research posters, and grant proposals (NSF, NIH, DOE, DARPA). This skill should be used when preparing manuscripts for journal submission, conference papers, research posters, or grant proposals and need venue-specific formatting requirements and templates.

Generalscripts

let-fate-decide

Included

Draws the 12 Houses of the Zodiac Tarot spread to inject entropy into planning when prompts are vague, ambiguous, or casually delegated. Interprets the spread to guide next steps. Use when the user says 'let fate decide', 'YOLO', 'whatever', 'idk', or other nonchalant phrases, makes Yu-Gi-Oh references, or when you are about to arbitrarily pick between multiple reasonable approaches. Prefer over ask-questions-if-underspecified when the user's tone is casual or playful rather than precision-seeking.

Generalscripts

net-ops

Included

Cross-platform network troubleshooting (Windows, macOS, Linux) via local or remote shell. Use for: DNS broken, can't resolve hostnames, nslookup/dig works but apps fail, NRPT, WFP, scutil, /etc/resolver, systemd-resolved, /etc/resolv.conf, NetworkManager, VPN DNS leak residue (ProtonVPN/Mullvad/WireGuard/AnyConnect), AV/firewall blocking DNS or DoH, Tailscale DNS interaction, intermittent connectivity, remote diagnostics over SSH.

Generalscripts