pubmed-database
# PubMed Database
What this skill does
# PubMed Database Direct REST API access to the National Library of Medicine's biomedical literature repository for systematic reviews and research analysis. ## Triggers - User asks to search for medical/scientific literature - User needs to find research papers on a cardiology topic - User wants to build a literature review - User requests evidence for a clinical claim - User needs citations for an article or newsletter ## Core Capabilities ### Search Construction Build sophisticated queries combining: - Boolean operators (AND, OR, NOT) - Field tags: `[mh]` for MeSH terms, `[au]` for author, `[ti]` for title, `[tiab]` for title/abstract - Publication filters by date, type, and availability ### E-utilities API Endpoints | Endpoint | Purpose | |----------|---------| | ESearch | Search and retrieve PMIDs | | EFetch | Retrieve full records | | ESummary | Get document summaries | | EPost | Upload ID lists | | ELink | Find related articles | **Rate limits**: 3 requests/second (10 with API key) ### Filtering Options - Publication type (clinical trials, systematic reviews, meta-analyses) - Date ranges - Text availability (free full text, abstracts) - Species (human studies) ### Citation Export Formats - NBIB (for reference managers) - AMA, MLA, APA, Vancouver styles - BibTeX for LaTeX ## Example Queries ### Cardiology-Specific Searches ``` # Recent SGLT2 inhibitor trials in heart failure "SGLT2 inhibitors"[mh] AND "heart failure"[mh] AND "clinical trial"[pt] AND "2023"[dp]:present[dp] # Interventional cardiology systematic reviews "percutaneous coronary intervention"[mh] AND "systematic review"[pt] # TAVR outcomes "transcatheter aortic valve replacement"[tiab] AND (outcomes[tiab] OR mortality[tiab]) ``` ### Building Evidence for Content 1. Start with MeSH terms for precision 2. Add free-text synonyms for coverage 3. Filter by publication type and recency 4. Review abstracts for relevance 5. Extract key findings with PMIDs for citation ## Workflow Integration When writing cardiology content: 1. Use this skill to find supporting evidence 2. Document PMIDs for all factual claims 3. Prefer systematic reviews and meta-analyses 4. Include recent trials (last 2-3 years) for currency 5. Cross-reference with citation-management skill for formatting ## Best Practices - Always verify claims with primary sources - Note study limitations when citing - Distinguish between observational and RCT evidence - Use MeSH terms for reproducible searches - Document search strategy for transparency
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